Cast
Chris Rock
Osmosis Jones (voice)
Laurence Fishburne
Thrax (voice)
David Hyde Pierce
Drix (voice)
Brandy Norwood
Leah (voice)
Bill Murray
Frank Detorre
Molly Shannon
Mrs. Boyd
William Shatner
Mayor Phlegmming (voice)
Ron Howard
Tom Colonic (voice)
Sherry Lynn
(voice)
Mickie McGowan
Additional Character Voice (voice)
Chris Elliott
Bob
Elena Franklin
Shane Detorre
Kid Rock
Kidney Rock
Uncle Kracker
Kidney Rock (voice)
Carlos Alazraqui
Additional Character Voices (voice)
Rodger Bumpass
Additional Character Voices (voice)
Richard Steven Horvitz
Additional Character Voices (voice)
Danny Mann
Additional Character Voices (voice)
Mickie McGowan
Additional Character Voices (voice)
Jonathan Adams
Additional Character Voices (voice)
Crew
Bobby Farrelly
Producer
(Production)
Lois Freeman-Fox
Editor
(Editing)
Bobby Farrelly
Director
(Directing)
Randy Edelman
Original Music Composer
(Sound)
Zak Penn
Producer
(Production)
Stephen Schaffer
Editor
(Editing)
Marc Hyman
Screenplay
(Writing)
Sam Seig
Editor
(Editing)
Peter Farrelly
Producer
(Production)
Mark Irwin
Director of Photography
(Camera)
Bradley Thomas
Producer
(Production)
Peter Farrelly
Director
(Directing)
Adam Beck
Animation
(Visual Effects)
Jeannine Berger
Post Production Supervisor
(Crew)
Paul Dutton
Animation
(Visual Effects)
Audrey Stedman
Layout
(Directing)
Bob Camp
Storyboard
(Writing)
Karen Hamrock
Layout
(Directing)
Eddie Rosas
Animation
(Visual Effects)
Jennifer Yuan
Layout
(Directing)
Bill Perkins
Layout
(Directing)
Earl A. Hibbert
Visual Effects
(Visual Effects)
Hani D. El-Masri
Visual Development
(Visual Effects)
Steve Fonti
Storyboard
(Writing)
John Bermudes
Special Effects
(Crew)
William 'Billy Jack' Jakielaszek
Special Effects Coordinator
(Crew)
Arlan Jay Vetter
Art Direction
(Art)
Chris Aguirre
Visual Development
(Visual Effects)
Mark Andrews
Storyboard
(Writing)
Carol Koch
Sculptor
(Art)
Kevin Johnson
Visual Development
(Visual Effects)
Marc S. Fischer
Co-Producer
(Production)
Barry Caldwell
Storyboard
(Writing)
Ruben Chavez
Visual Development
(Visual Effects)
Katherine C. Concepcion
Art Department Manager
(Art)
Daan Jippes
Storyboard
(Writing)
Aaron Parry
Associate Producer
(Production)
Darek Gogol
Visual Development
(Visual Effects)
John Harajovic
Special Effects
(Crew)
Ricardo F. Delgado
Visual Development
(Visual Effects)
Leon Delaney
Stunt Coordinator
(Crew)
John Walker
Associate Producer
(Production)
Jeff Etter
Visual Development
(Visual Effects)
Craig R. Maras
Animation
(Visual Effects)
Randy Sanchez
Animation
(Visual Effects)
James P. Alles
Layout
(Directing)
John Williamson
Animation
(Visual Effects)
Joe Giampapa
Animation
(Visual Effects)
Sam Chou
Animation
(Visual Effects)
Shane Prigmore
Animation
(Visual Effects)
Fred Cline
Visual Development
(Visual Effects)
Brenda McNally
Hair Department Head
(Costume & Make-Up)
Hal Olofsson
First Assistant Director
(Directing)
Pamela Withers
Costume Design
(Costume & Make-Up)
Sydney J. Bartholomew Jr.
Production Design
(Art)
Ian Mah
Visual Effects Supervisor
(Visual Effects)
Darlie Brewster
Supervising Animator
(Crew)
Steven Burch
Special Effects Supervisor
(Visual Effects)
Joe Rossi
Makeup Department Head
(Costume & Make-Up)
Randy Thom
Sound Designer
(Sound)
Stephan Franck
Lead Animator
(Visual Effects)
Ken Ross
Music Supervisor
(Sound)
Scott Jacobson
Set Decoration
(Art)
Rick Montgomery
Casting
(Production)
Dennis Edwards
Producer
(Production)
Alan J. Hagge
Systems Administrators & Support
(Crew)
Louis Gonzales
Layout
(Directing)
Moroni Taylor
Storyboard Artist
(Art)
Ricardo Curtis
Supervising Animator
(Crew)